gdb will not run and hit breakpoints

I am using unix with a project that deals with C++ source files.

In the directoryuser/project/Build, I enter make to compile and link the source files and then go to user/run and enter run.sh test.txt to run the program

After I go to /user/project/Build/bin and enter gdb project and then run, I always get the message Program exited with code 01. Missing separate debuginfos, use: debuginfo-install glibc.

Although I can set breakpoints in main.cpp, if I enter 'break foo.cpp:19', I see No source file named foo.cpp. Make breakpoint pending on future shared library load? But this is wrong because I have foo.cpp

When I head to Build and try cmake -DCMAKE_BUILD_TYPE:STRING=Debug ../src, I receive looking for pthread_create - not found. -- Found Threads: TRUE CMake Error at log4cplus/CMakeLists.txt:152 (SetupBoost): Unknown CMake command "SetupBoost". -- Configuring incomplete, errors occurred!. The problem does not get resolved even if I edit the Makefile to include the CXXFLAGS

What is going on?