2D Desktop Application Engine

Okay I know this is some kind of "What library should I use?" but please hear me out and understand that the main problem for my question are games. Because whenever I try to do my research I end up walking through the API of another game engine. So I hope this one gets through:

I want to write an application for presentations and knowledge management. I've already found some useful libraries for the "multi platform native UI stuff" and things but what I can't seem to find is something like a "2D Desktop Application Engine".

I am talking about a library or an engine that will help me to create a desktop-like environment. What I mean by that is e.g. that I don't want to have to take care e.g. about clicking events, window-message passing and/or window ordering and basic stuff like that. But on the other hand it should not restrict me from anything design related.

At some point I was already thinking about using a 2D game engine for such a task but I am afraid that I'd have to implement the "desktop-like-behavior" part myself and this just does not feel right in the year of 2015.

So does anybody know a library that would fulfill my needs? Best regards and thank you for any help!